Welcome to the Department of Biology

Department of Biology at Illinois State University
Department of Biology

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Dr. Nate Mortimer

Assistant Professor of Cellular Immunology
  • CURRENT COURSES
  • BSC 290.Sec 047 Research In Biological Sciences
  • TEACHING INTERESTS
  • My teaching interests include: Cell Biology, Immunology, Comparative Immunology, Genetics
  • RESEARCH INTERESTS
  • Research in my lab is focused on understanding cellular immune responses, and uncovering the tricks that pathogens and parasites use to overcome them. We use the fruit fly Drosophila melanogaster and parasitoid wasps that infect flies as a model host-parasite system. Projects in the lab include: the molecular genetics of cellular immunity, parasite virulence mechanisms, and the genetics of autoimmunity.
  • Ph D Genetics and Molecular Biology - 2009
  • Emory University
  • Atlanta, GA
  • BS Biology - 2000
  • Emory University
  • Atlanta, GA
  • SELECTED PUBLICATIONS
  • Schachtner, L.T., I.E. Sola, D. Forand, S. Antonacci, A.J. Postovit, N.T. Mortimer, D.J. Killian and E.C. Olesnicky. 2015. Drosophila Shep and C. elegans SUP-26 are RNA-binding proteins that play diverse roles in nervous system development. Development Genes and Evolution, in press.

  • Antonacci, S., D. Forand, M. Wolf, C. Tyus, J. Barney, L. Kellogg, M. Simon, G. Kerr, N.T. Mortimer, E.C. Olesnicky and D.J. Killian. 2015. Conserved RNA-Binding Proteins are Required for Dendrite Morphogenesis in Caenorhabditis elegans Sensory Neurons. G3: Genes, Genomics, Genetics 5(4): 639-53.

  • Vrailas-Mortimer, A., Ryan, S., Avey, M., Mortimer, N., Dowse, H. and Sanyal, S. The p38 MAP Kinase regulates circadian rhythm in Drosophila. Journal of Biological Rhythms. 2014 Dec;29(6):411-26.
  • Mortimer, N.T. 2013. Parasitoid wasp virulence: a window into fly immunity. Fly 7(4), 242-248.

  • Mortimer, N.T., J. Goecks, B.Z. Kacsoh, J.A. Mobley, G.J. Bowersock, J. Taylor and T.A. Schlenke. 2013. Parasitoid wasp venom SERCA regulates Drosophila calcium levels and inhibits cellular immunity. Proceedings of the National Academy of Sciences USA (PNAS) 110(23): 9427-9432.

  • Goecks, J., N.T. Mortimer, J.A. Mobley, G.J. Bowersock, J. Taylor and T.A. Schlenke. 2013 Integrative approach reveals composition of endoparasitoid wasp venoms. PLOS One 8(5): e64125.

  • Kacsoh, B.Z., Z.R. Lynch, N.T. Mortimer, and T.A. Schlenke. 2013. Fruit flies medicate offspring after seeing parasites. Science 339(6122): 947-950.

  • Mortimer, N.T. and K.H. Moberg. 2013. The archipelago ubiquitin ligase subunit acts in target tissue to restrict tracheal terminal cell branching and hypoxic-induced gene expression. PLOS Genetics 9(2): e1003314.

  • Mortimer, N.T., B.Z. Kacsoh, E.S. Keebaugh and T.A. Schlenke. 2012. Mgat1-dependent N-glycosylation of membrane components primes Drosophila melanogaster blood cells for the cellular encapsulation response. PLOS Pathogens 8(7): e1002819.

  • Mortimer, N.T. and K.H. Moberg. 2009. Regulation of Drosophila embryonic tracheogenesis by dVHL and hypoxia. Developmental Biology 329(2): 294-305.

  • Mortimer, N.T. and K.H. Moberg. 2007. The Drosophila F-box protein Archipelago controls levels of the Trachealess transcription factor in the embryonic tracheal system. Developmental Biology 312(2): 560-571.

  • Suli, A., N.T. Mortimer, I. Shepherd and C.B. Chien. 2006. Netrin/DCC signaling controls contralateral dendrites of octavolateralis efferent neurons. Journal of Neuroscience 26(51): 13328-13337.

  • Rogers, E.M., C.A. Brennan, N.T. Mortimer, S. Cook, A.R. Morris and K. Moses. 2005. Pointed regulates an eye-specific transcriptional enhancer in the Drosophila hedgehog gene, which is required for the movement of the morphogenetic furrow. Development 132(21): 4833-4843.

  • Yedvobnick, B., A. Kumar, P. Chaudhury, J. Opraseuth, N.T. Mortimer and K.M. Bhat. 2004. Differential effects of Drosophila mastermind on asymmetric cell fate specification and neuroblast formation. Genetics 166(3): 1281-1289.

  • PRESENTATIONS
  • FUNDED GRANTS