Dr. John Sedbrook
Professor of Genetics
Office
SLB Science Laboratory Building 127
Office Phone
Email
- About
- Education
- Awards & Honors
- Selected Research
Current Courses
BSC 203.001 Cell Biology
BSC 299.005 Independent Honor Study
BSC 499.008 Independent Research For The Master's Thesis
BSC 499.108 Independent Research For The Master's Thesis Last Term
BSC 290.027 Research In Biological Sciences
BSC 599.008 Research In The Biological Sciences
BSC 599.108 Research In The Biological Sciences Final Term
BSC 420.001 Seminar In Molecular & Cellular Biology
Ph D Genetics
University of Wisconsin-Madison
Induction into the ISU $1 million Club
Illinois State University
2012
Grants and Contracts
Interrogating pennycress natural and induced variation to improve abiotic stress tolerance and oilseed bioenergy crop resilience
John Sedbrook, Wondwosen Seyoum.
U.S. Department of Energy. 2020 - 2025
Interrogating pennycress natural and induced variation to improve abiotic stress tolerance and oilseed bioenergy crop resilience
John Sedbrook, Moises Exposito-Alonso, Sue Rhee, David Marks, Dmitri Nusinow, Christopher Topp, Daniel Jacobson, Pubudu Handakumbura, Winthrop Phippen, Karen Sanguinet, Andrea Gschwend.
DOE BER. September 15 2020 - September 14 2025
Oilseed Pennycress: A new cash cover-crop for the Midwest $10,000,000
Win Phippen, John Sedbrook, William Hunter, William Perry, Alex Lindsay, Scott Wells, David Marks.
US Department of Agriculture. August 2019 - August 2024
Genetic improvement of seed yield and oil content in field pennycress, a non-food oilseed feedstock.
John Sedbrook.
USDA. December 2018 - December 2021
MRI: Acquisition of a laser scanning confocal microscope within a core facility for research and training at Illinois State University
Kevin Andrew Edwards, Wolfgang Stein, Tom Hammond, Alysia Vrailas Mortimer, John Sedbrook, Andres Vidal-Gadea, Marjorie Jones.
National Science Foundation. October 1 2018 - September 30 2022
Advancing field pennycress as a new oilseed biodiesel feedstock that does not require new land commitments. $1 million collaborative grant ($367,021 to Sedbrook)
John Sedbrook.
USDA. September 1 2014 - August 31 2017
Great Lakes Bioenergy Research Center (5 year, $125 million renewal)
John Sedbrook.
Department of Energy-GTL. December 1 2012 - November 30 2017
Intellectual Property
Liquid and Semisolid Lubricant Compositions and Methods of Making, and Uses Thereof.
United States 63/585,082
Diana Berman, Asghar Shirani, Rawan Al Sulaimi, Kent Chapman, John Sedbrook.
p-Coumaroyl-CoA:Monolignol Transferase
United States 61/576,515,
John Sedbrook, Curtis Wilkerson, John Ralph, Saunia Withers.
Journal Article
Chromosome-level Thlaspi arvense genome provides new tools for translational research and for a newly domesticated cash cover crop of the cooler climates
Adam Nunn, Isaac Rodríguez-Arévalo, Zenith Tandukar, Katherine Frels, Adrián Contreras-Garrido, Pablo Carbonell-Bejerano, Panpan Zhang, Daniela Ramos-Cruz, Katharina Jandrasits, Christa Lanz, Anthony Brusa, Marie Mirouze, Kevin Dorn, Brice Jarvis, John Sedbrook, Donald Wyse, Christian Otto, David Langenberger, Peter Stadler, Detlef Weigel, M. David Marks, James Anderson, Claude Becker, Ratan Chopra.
Plant Biotechnology Journal, DOI: 10.1111/pbi.13775, (2022)
Analysis of formin functions during cytokinesis using specific inhibitor SMIFH2.
Laining Zhang, Tetyana Smertenko, Deirdre Fahy, Nuria Koteyeva, Natalia Moroz, Anna Kuchařová, Dominik Novák, Eduard Manoilov, Petro Smertenko, Charitha Galva, Jozef Šamaj, Alla S. Kostyukova, John Sedbrook, Andrei Smertenko.
(2021)
Brachypodium phenylalanine ammonia lyase (PAL) promotes antiviral defenses against Panicum mosaic virus and its satellites.
Shankar R. Pant, Sonia Irigoyen, Jiaxing Liu, Renesh Bedre, Shawn A. Christensen, Eric A. Schmelz, John Sedbrook, Karen-Beth G. Scholthof, Kranthi K. Mandadia.
(2021)
Generating pennycress (Thlaspi arvense) seed triacylglycerols and acetyl-triacylglycerols containing medium-chain fatty acids.
Maliheh Esfahanian, Tara Nazarenus, Meghan Freund, Gary McIntosh, Winthrop Phippen, Mary Phippen, Timothy Durrett, Edgar Cahoon, John Sedbrook.
Frontiers in Energy Research, (2021)
Assessing the Viability of Recovery of Hydroxycinnamic Acids from Lignocellulosic Biorefinery Alkaline Pretreatment Waste Streams
Steven Karlen, Peyman Fasahati, Mona Mazaheri, Rebecca Smith, Cynthia Cass, Sirisha Sirobhushanam, Mingjie Chen, Vitaliy Tymokhin, Sarah Liu, Dharshana Padmakshan, Jose Serate, Dan Xie, Yaoping Zhang, Mick Mcgee, Cliff Foster, Jason Russell, Heidi Kaeppler, Natalia de Leon, Christos Maravelias, Troy Runge, Shawn Kaeppler, John Sedbrook, John Ralph.
(2020)
Identification and stacking of crucial traits required for the domestication of pennycress
Ratan Chopra, E. Johnson, R. Emenecker, Edgar Cahoon, Joseph Lyons, Daniel Kliebenstein, E. Daniels, Kevin Dorn, Maliheh Esfahanian, Nicole Folstad, Katherine Frels, Michaela McGinn, Matthew Ott, C. Gallaher, K. Altendorf, Alexandra Berroyer, B. Ismail, James Anderson, Donald Wyse, Timothy Ulmasov, John Sedbrook, M. David Marks.
Nature Food, (2020)
Pennycress, carbon wise: labeling experiments reveal how pennycress seeds efficiently incorporate carbon into biomass.
John Sedbrook, Timothy P. Durrett.
Journal of Experimental Botany, (2020)
CLASP stabilization of plus ends created by severing promotes microtubule creation and reorientation
Jelmer J Lindeboom, Masayoshi Nakamura, Marco Saltini, Anneke Hibbel, Ankit Walia, Tijs Ketelaar, Anne Mie C Emons, John Sedbrook, Viktor Kirik, Bela M Mulder, David W Ehrhardt.
Journal of Cell Biology, 218 (1), 190-205, (2019), 10.1083/jcb.201805047
Suppression of CINNAMOYL-CoA REDUCTASE increases the level of monolignol ferulates incorporated into maize lignins.
Rebecca Smith, Cynthia Cass, Mona Mazaheri, Rajan Sekhan, Marlies Heckwolf, Heidi Kaeppler, de Leon Natalia, Shawn Mansfield, Shawn Kaeppler, John Sedbrook, Steven Karlen, John Ralph.
Biotechnology for Biofuels, 10 (109), (2017)
BdCESA7, BdCESA8, and BdPMT utility promoter constructs for targeted expression to secondary cell-wall forming cells of grasses.
Deborah Petrik, Cynthia Cass, Darshana Padmakshan, Cliff Foster, John Vogel, Steven Karlen, John Ralph, John Sedbrook.
Frontiers in Plant Science, 7 (55), (2016), doi: 10.3389/fpls.2016.00055
Cell Wall Composition and Biomass Recalcitrance Differences Within a Genotypically Diverse Set of Brachypodium distachyon Inbred Lines
Cynthia Cass, Anastasiya Lavell, Nicholas Santoro, Cliff Foster, Steven Karlen, Rebecca Smith, John Ralph, David Garvin, John Sedbrook.
Frontiers in Plant Science, 7 (708), (2016), 10.3389/fpls.2016.00708
Monolignol ferulate conjugates are naturally incorporated into plant lignins.
S. D. Karlen, C. Zhang, M. L. Peck, R. A. Smith, D. Padmakshan, K. E., H. C.A., S. Lee, B. B. Smith, F. Lu, John Sedbrook, R. Sibout, J. H. Grabber, T. M. Runge, K. S. Mysore, P. J. Harris, L. E. Bartley, J. Ralph.
Science Advances, 2, e1600393, (2016)
Sustainable commercialization of new crops for the agricultural bioeconomy
N.R. Jordan, K. Dorn, B. Runck, P. Ewing, A. Williams, K.A. Anderson, L. Felice, K. Haralson, J. Goplen, John Sedbrook, M. D. Marks, K. Wolf, D. Wyse, G. Johnson.
Elementa: Science of the Anthropocene., 4 (000081), (2016), 10.12952/journal.elementa.000081
Ectopic expression of WRI1 affects fatty acid homeostasis in Brachypodium distachyon vegetative tissues.
Yang Yang, Jacob Munz, Cynthia Cass, Agnieszka Zienkiewicz, Que Kong, Wei Ma, Sanjaya Sanjaya, John Sedbrook, Christoph Benning.
Plant Physiology, 169, 1836-1847, (2015)
Effects of PHENYLALANINE AMMONIA LYASE (PAL) knockdown on cell wall composition, biomass digestibility, and biotic and abiotic stress responses in Brachypodium.
Cynthia Cass, A Peraldi, P F Dowd, Y Mottiar, N Santoro, S D Karlen, Y V Bukhman, C E Foster, N Thrower, L C Bruno, O V Moskvin, E T Johnson, M E Willhoit, M Phutane, J Ralph, S D Mansfield, P Nicholson, John Sedbrook.
Journal of experimental botany, 66 (14), 4317-35, (2015), 10.1093/jxb/erv269
New approaches to facilitate rapid domestication of a wild plant to an oilseed crop: example pennycress (Thlaspi arvense L.).
John Sedbrook, W. Phippen, M. D. Marks.
Plant Science, 227, 122-132, (2014)
The Microtubule Plus-End Tracking Proteins SPR1 and EB1b Interact to Maintain Polar Cell Elongation and Directional Organ Growth in Arabidopsis.
C Galva, Viktor Kirik, J Lindeboom, D Kaloriti, D Rancour, P Hussey, S Bednarek, D Ehrhardt, John Sedbrook.
The Plant Cell, 26, 4409-4425, (2014)
p-Coumaroyl-CoA:Monolignol Transferase (PMT) acts specifically in the lignin biosynthetic pathway in Brachypodium distachyon
D Petrik, S Karlen, C Cass, D Padmakshan, F Lu, S Liu, P Le Bris, S Antelme, N Santoro, C Wilkerson, R Sibout, C Lapierre, J Ralph, John Sedbrook.
The Plant Journal, 77, 713-726, (2014)
p-Coumaroyl-CoA:monolignol transferase (PMT) acts specifically in the lignin biosynthetic pathway in Brachypodium distachyon.
D L Petrik, S D Karlen, Cynthia Cass, D Padmakshan, F Lu, S Liu, P Le Bris, S Antelme, N Santoro, C G Wilkerson, R Sibout, C Lapierre, J Ralph, John Sedbrook.
The Plant journal : for cell and molecular biology, 77 (5), 713-26, (2014), 10.1111/tpj.12420
Brachypodium as a model for the grasses: Today and the future
J Brkljacic, ..., John Sedbrook, et al..
Plant Physiology, 157, 3-13, (2011)
Genome Sequencing and Analysis of the Model Grass Brachypodium distachyon
J Vogel, ..., John Sedbrook, et al..
Nature, 463 (763-768), (2010)
Impact of selected cultural practices on seedling growth of Osage orange (Maclura pomifera)
J D Rozum, D E Kopsell, G R Bachman, B R Wiegand, John Sedbrook, R L Rhykerd.
Transactions of the Illinois State Academy of Science, 103, 1-12, (2010)
A role for the TOC complex in Arabidopsis root gravitropism
J P Stanga, K Boonsirichai, John Sedbrook, M S Otegui, P H Masson.
Plant Physiology, 149, 1896-1905, (2009)
Anaerobic digestion of cereal rye cover crop
Liangcheng Yang, Lucas Lamont, John Sedbrook, Nicholas Heller, David Kopsell.
Fermentation, https://doi.org/10.3390/ fermentation8110617
Presentations
Developing pennycress into an oilseed cash cover crop named CoverCress.
John Sedbrook.
ISU Community partners Breakfast hosted by President Kinzy, ISU Bone Student Center, Normal, IL, May 13, 2022
Using agricultural biotechnology to rapidly domesticate pennycress and the opportunity that this cover crop and oilseed crop has to mitigate climate change
John Sedbrook.
Asia-Pacific Economic Cooperation High Level Policy Dialogue on Agricultural Biotechnology, Online (Malaysia), April 19, 2022
Gene editing in Pennycress, a new oilseed cash cover crop
John Sedbrook.
Gene Edited Plants: Context and Communication for Plant Breeding Innovation, Webinar for stakeholders in South Korea, July 19, 2021
Acceptance of gene edited crops for regenerative agriculture.
John Sedbrook.
Cooperative Governance Pilot Project: Gene Editing Crops for Regenerative Agriculture, Zoom, University of Minnesota, May 13, 2021
Covercress (domesticated pennycress) Economic, environmental, and societal opportunities throughout Illinois.
John Sedbrook.
Briefing, Illinois Farm Bureau, Bloomington, IL, October 29, 2019
From Weed to Cash: Researchers Genetically Engineer Pennycress.
John Sedbrook.
WGLT News story on USDA funding of $10 million IPREFER project, Illinois State University, October 3, 2019
ISU researchers see potential to make dollars with pennycress.
John Sedbrook, Maliheh Esfahanian, Brice Jarvis, Dalton Williams.
Pantagraph News story on USDA funding of $10 million IPREFER project, School of Biological Sciences, Illinois State University, October 2, 2019
https://isu10news.com/tv-10-news-wednesday-september-18-2019/
John Sedbrook.
TV-10 News story on USDA funding of $10 million IPREFER project, School of Biological Sciences, September 18, 2019
Covercress (domesticated pennycress) Economic, environmental, and social opportunities throughout Illinois.
John Sedbrook.
Lab/facilities tour and briefing to U.S. Congressional Representative Rodney Davis, State of Illinois Senate Minority Leader Bill Brady, and State of Illinois Representative Dan Brady, School of Biological Sciences, Illinois State University, August 20, 2019
Innovation in Agriculture: What Does Gene Editing Mean for the Future?
John Sedbrook.
House Agriculture Research Caucus, Washington D.C. Capital Hill, Washington D.C. Capital Hill, July 16, 2019
Pennycress as a Cash Cover Crop:Value Proposition
John Sedbrook.
Cooperative Governance Workshop on gene editing, University of Minnesota, June 3, 2019
Progress in developing pennycress as an oilseed cash cover crop.
John Sedbrook.
Western Illinois University Pennycress Field Day, Macomb, IL, May 23, 2019
Pennycress as a new oilseed cash cover crop
John Sedbrook.
ISU Farm Field Day, Lexington, IL, April 20, 2019
Prospects for developing pennycress, an Arabidopsis relative, as a new winter annual oilseed energy crop.
John Sedbrook.
Energy Biosciences Institute, University of California, Berkeley., Berkeley, CA, June 25, 2015