Dr. Thomas Hammond    

Publications (by Subject Area)


Hammond, T.M., H. Xiao, D.G. Rehard, and P.K.T. Shiu (2011) "Fluorescent and bimolecular-fluorescent protein tagging of genes at their native loci in Neurospora crassa using specialized double-joint PCR plasmids." Fungal Genet. Biol. 48:866-73. [PMID: 21664475]

Smith, Z. J., S. Bedore, S. Spingler, and T. M. Hammond (2016)  "A mus-51 RIP allele for transformation of Neurospora crassa." Fungal Genet. Rep. 62:1-7. https://doi.org/10.4148/1941-4765.1001

Rhoades, N.A., Elise K. Webber, and T. M. Hammond (2020) “A nonhomologous end-joining mutant for Neurospora sitophila research.” Fungal Genet. Rep. Vol 64: Article 1. https://doi.org/10.4148/1941-4765.2172

Heterologous expression in fungi

Burrell,, N., N. A. Rhoades, A. Boyd, J. Mierendorf, A. Yusifov, A. Harvey, K. Edwards, L. Vogel, and T. M. Hammond (2020) “Investigating expression of a human optimized cas9 transgene in Neurospora crassa” BioRXiv https://doi.org/10.1101/2020.12.29.424703


Meiotic Silencing by Unpaired DNA (MSUD)

Alexander, W.G., N.B. Raju, H. Xiao, T.M. Hammond, T.D. Perdue, R.L. Metzenberg, P.J. Pukkila, and P.K.T. Shiu (2008) "DCL-1 colocalizes with other components of the MSUD machinery and is required for silencing" Fungal Genet. Biol. 45:719-27. [PMID: 18036854]

Xiao, H., W.G. Alexander, T.M. Hammond, E.C.  Boone, T.D. Perdue, P.J.  Pukkila, and P.K.T. Shiu (2010) "QIP, a protein that converts duplex siRNA into single strands, is required for meiotic silencing by unpaired DNA" Genetics 186:119-26. [PMID: 20551436]

Hammond, T.M., H. Xiao, E.C. Boone, T.D. Perdue, P.J. Pukkila, and P.K.T. Shiu (2011) "SAD-3, a Putative Helicase Required for Meiotic Silencing by Unpaired DNA, Interacts with Other Components of the Silencing Machinery" G3 1:369-376.[PMID: 22384347]

Hammond, T.M., H. Xiao, E. C. Boone, L. M. Decker, S. A. Lee, T. D. Perdue, P. J. Pukkila, and P.K.T. Shiu (2013) "Novel Proteins Required for Meiotic Silencing by Unpaired DNA and siRNA Generation in Neurospora crassa" Genetics, 194:91-100. [PMID:23502675]

Hammond, T.M., W.G. Spollen, L.M. Decker, S. M. Blake, G.K. Springer P.K.T. Shiu (2013) "Identification of Small RNAs Associated with Meiotic Silencing by Unpaired DNA" Genetics, 194:279–284. [PMID:23502674]

Samarajeewa, D. A., P. A. Sauls, K. J. Sharp, Z. J. Smith, H. Xiao, T. L. Malone, E. C. Boone, K. A. Edwards, P. K. T. Shiu, E. D. Larson, and T. M. Hammond (2014)  “Efficient detection of unpaired DNA requires a member of the Rad54-Like Family of homologous recombination proteins”Genetics 198:895-904. [PMID:25146971]

Samarajeewa, D.A., P. Manitchotpisit, M. Henderson, H. Xiao, D.G. Rehard, K.A. Edwards, P.K.T. Shiu, and T. M. Hammond (2017)   "An RNA recognition motif-containing protein functions in meiotic silencing by unpaired DNA." G3 7:2871-2882. [PMID: 28667016]

Hammond, T. M. (2017)   "Sixteen years of meiotic silencing by unpaired DNA", In T. Friedman, J. C. Dunlap & S. F. Goodwin (Eds.) Advances in Genetics 97:1-42. [PMID: 28838355]

Rhoades, N., T-S Nguyen, G. Witz, G. Cecere, T. Hammond, A. Mazur, E. Galdyshev (2021) "Recombination-independent recognition of DNA homology for meiotic silencing in Neurospora crassa" PNAS 118(33) e2108664118 PMID: 34385329 https://doi.org/10.1073/pnas.2108664118


Spore Killing

Hammond, T.M., D.G. Rehard, B.C.Harris, and P.K. Shiu (2012) "Fine-scale mapping in Neurospora crassa by using genome-wide knockout strains." Mycologia. 104(1):231-3. [PMID: 22067301]

Hammond, T.M., D.G. Rehard, H. Xiao, and P.K.T. Shiu (2012) "Molecular dissection of Neurospora Spore killer meiotic drive elements" Proc. Natl. Acad. Sci. U.S.A, 109:12093-12098. [PMID: 22753473]

Harvey, A. M., D. G. Rehard, K. M. Groskreutz, D. R. Kuntz, K. J. Sharp, P. K. T. Shiu, and T. M. Hammond (2014) “A Critical Component of Meiotic Drive in Neurospora Is Located Near a Chromosome Rearrangement” Genetics 197:1165-1174. [PMID:24931406]

Pyle, J., T. Patel, B. Merrill, C. Nsokoshi, M. McCall, R. H. Proctor, D. W. Brown, and T. M. Hammond (2016) " A meiotic drive element in the maize pathogen Fusarium verticillioides is located within a 102-kb region of chromosome V" G3 6(8)2543-52. [PMID:27317777]

Svedberg, J., S. Hosseini, J. Chen, A. Vogan, I. Mozgova, L. Hennig, P. Manitchotpisit, A. Abusharekh, T. Hammond, M. Lascoux, and H. Johannesson (2018) “Convergent evolution of complex rearrangements in two fungal meiotic drive elements” Nature comm. 9: Article 4242. [PMID: 30315196]

Rhoades, N.A, A.M. Harvey, D.A. Samarajeewa, J. Svedberg, A. Yusifov, A. Abusharekh, P. Manitchotpisit, D. W. Brown, K. J. Sharp, D. G. Rehard, J. Peters, X. Ostolaza-Maldonado, J. Stephenson, P. K. T. Shiu, H. Johannesson, and T. M. Hammond (2019) “Identification of rfk-1, a Meiotic Driver Undergoing RNA Editing in Neurospora” Genetics 212:93-110. [PMID: 30918007]

Svedberg, J., A. A. Vogan, N. A. Rhoades, D. Sarmarajeewa, D. J. Jacobson, M.  Lascoux, T. M. Hammond, and H. Johannesson (2021) “An introgressed gene causes meiotic drive in Neurospora sitophila” Proceedings of the National Academy of Sciences Apr 2021, 118 (17) e2026605118. [PMID: 33875604]

Lohmar, J.M., N.A. Rhoades, T. N. Patel, R. H. Proctor, T. M. Hammond, D. W. Brown (2022) "A-to-I mRNA editing controls spore death induced by a fungal meiotic drive gene in homologous and heterologous expression systems" Genetics PMID: 35166849 DOI: 10.1093/genetics/iyac029 (Online ahead of print)



RNA Silencing and Mycoviruses

Hammond, T.M., and N.P. Keller (2005) "RNA silencing in Aspergillus nidulans is independent of RNA dependent RNA polymerases" Genetics 169:607-617. [PMID: 15545645]

Hammond, T.M., J.W. Bok, M.D. Andrewski, Y. Reyes-Domínguez, C. Scazzocchio, and N.P. Keller (2008) "RNA silencing gene truncation in the filamentous fungus Aspergillus nidulans" Euk. Cell 7:339-49. [PMID: 18065653]

Hammond, T.M., M.D. Andrewski, M.J. Roossinck, and N.P. Keller (2008) "Aspergillus mycoviruses are targets and suppressors of RNA silencing" Euk. Cell 7:350-357. [PMID: 18065651]

Host-Microbe Interactions

McDonald, T.R., D. Brown, N.P. Keller, and T.M. Hammond (2005) "RNA silencing of mycotoxin production in Fusarium and Aspergillus species" Mol. Plant Microbe Int. 18:539-545. [PMID: 15986923]

Hammond, T.M., D. Tsitsigiannis, and N.P. Keller (2007) "Development of an Arabidopsis thaliana-based bioassay for investigating seed colonization by mycotoxigenic Aspergillus species" Plant Pathol. 56:848-854. https://doi.org/10.1111/j.1365-3059.2007.01644.x

Scherm, B., M. Orru, V.  Balmas, F. Spanu, E. Azara, G. Delogu, T.M. Hammond, N.P. Keller, and Q. Migheli (2011) "Altered trichothecene biosynthesis in TRI6-silenced transformants of Fusarium culmorum influences the severity of crown and foot rot on durum wheat seedlings" Mol. Plant Pathol. 12:759-71. [PMID: 21726376]